COMPARATIVE STUDY OF Ricinus communis AND Elaeis guineensis OIL CONSUMPTION ON LIVER BIOMARKERS IN WISTAR RATS

ABSTRACT

Ricinus communis oil and Elaeis guineensis oil which are derived from castor bean and palm fruits are both edible vegetable oil. In this research, the Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) levels were determined in fifteen (15) wistar albino rats (4 groups of 4 rats each). Group A were fed with Elaeis guineensis oil, Group B were fed with Ricinus communis oil, Group C were fed with a mixture of both Elaeis guineensis oil and Ricinus communis oil, finally Group D were fed with the standard feed. The feeding lasted for 14 days after which the rats were sacrificed and their blood serum collected. The haematological parameters were determined using using an automated haematology analyzer. The result showed a significant (p<0.05) increase in ALT activity in animals fed with Elam’s guineensis oil compounded feed compared with the Manus communis group. Also there was a significant (p<0.05) increase in AST activity in animals fed with Elaels guineensis oil compounded feed compared with Ricinus communis group. The results in this research, suggest that lower level of ALT due to the intake of Ricinus communis can be clinical important in the treatment of obesity.